Cica + Niacinamide Sunscreen SPF 50+

Octinoxate and Octocrylene have demonstrated endocrine disrupting properties that may affect thyroid and reproductive hormone systems [1.1].

Powdered and aerosolized forms are classified as suspected carcinogens by inhalation and recent European assessments raised genotoxicity concerns regarding incidental oral ingestion [1.9].

Not approved by the US FDA as a sunscreen active and subject to strict EU impurity limits for the reproductive toxicant di n hexyl phthalate.

FDA clinical trials indicate that ecamsule can be absorbed into the bloodstream at levels exceeding the testing threshold prompting calls for further safety evaluation [2.9].

Not approved by the US FDA for use as an active sunscreen ingredient but is widely approved in the EU and other regions up to 5 percent.

The European Union is restricting this ingredient to a maximum concentration of one tenth of a percent in leave on cosmetics effective June 2027.

Structurally similar to octisalate, it has been flagged in predictive modeling studies for potential weak estrogen receptor binding activity.

Historically rated as mildly comedogenic in animal models but modern dermatological consensus indicates it is unlikely to clog pores in typical cosmetic formulations.

The ethoxylated components in this blend, such as Trideceth 6 and PEG PPG Dimethicone, may contain trace amounts of 1,4 dioxane, a potential carcinogen created during the manufacturing process [2.1].

The blend contains Polysorbate 20, an ethoxylated ingredient that may be contaminated with trace amounts of 1,4 dioxane, a probable carcinogen, as a byproduct of the ethoxylation manufacturing process [2.1].

Poorly biodegradable in the environment and can accumulate in aquatic ecosystems where it may mobilize heavy metals.

Both components are documented, albeit rare, contact allergens that can trigger allergic contact dermatitis in susceptible individuals.